If the game freezes, just click inside it (games can get unresponsive if you click elsewhere on the page).
Tickle the lady without getting caught. Move using mouse and tickle clicking left mouse button. If the lady catches you in the act, you will be slapped. 3 slaps and you are dead. If you succeed in tickling without getting noticed, a fellow passenger gets slapped. Once his life meter runs out, another passenger replaces him. Stay in the bus, tickle the lady and let somebody else get slapped before time runs.
This game is played with mouse only.